It's worth remembering that, although alcohol is a legal drug and can be purchased by any person over 18 years old, it can be a dangerous drug, particularly when abused.
Barbiturates and benzodiazepines are the two major categories of depressant drugs used as medicines. Often these drugs are referred to as sleeping pills and tranquilizers or sometimes just as sedatives. Some well-known barbiturates are secobarbital (Seconal) and pentobarbital (Nembutal). Benzodiazepines commonly in use are Diazepam (Vallium), chlordiazepoxide (Librium) Nitrazepam (Mogodon) and Temazepam.
Barbiturates used to be common drugs of abuse in the 1950's and 1960's but because of their addictive properties and association with suicides and accidental deaths, their use as medicines has been reduced significantly since the 1970's. The illicit market in these drugs has become smaller because of their reduced availablity.
Unfortunately, benzodiazepines - which were originally developed to provide a safe alternative to barbiturates for the treatment of anxiety and insomnia - have now become a major category of abused drugs. Vallium, Librium and Temazepam are the most commonly abused tranquillisers and are often taken with alcohol as these two types of drug amplify each others effect.
Regular use of all depressants over a long period of time can result in tolerance, which means a person has to take larger and larger doses to get the same effects. This includes alcohol. When regular users stop using large doses of these drugs suddenly, they may develop physical withdrawal symptoms ranging from restlessness, insomnia and anxiety, to convulsions and death.
Click on these links to see specific information about alcohol, barbiturates or tranquillisers.