Well - perhaps they ARE fed up with your behaviour - perhaps they've got good reason to be. But if so, it's your behaviour that they don't like. They probably still love YOU as a person.
If you talk to family members or friends honestly about your drug or alcohol problem - and are able to ask for their help in dealing with it - then you might be surprised at their reaction. Usually, if they think that you're being straight with them, your family or good friends will be happy to give you help and support.
But don't mess with them - they deserve respect.
If you're concerned about a family member who is abusing drugs or alcohol, family members and friends can give you emotional support that'll help you to cope with the situation. They can act as a shoulder to cry on - or as a physical support in confronting the abuser about his or her behaviour.
Maybe they can help you to find a way forward. A way of looking after yourself, while at the same time encouraging the drug/alcohol abuser to seek help.